Published Work

General publications

Molecular Recognition of PPAR# by the Kinase Cdk5/ p25

http://pubs.acs.org/doi/pdf/10.1021/acs.jpcb.5b04269

The peroxisome proliferatoractivated receptor γ (PPARγ) is an important transcription factor that plays a major role in the regulation of glucos e and lipid metabolisms and has, therefore, many implications in modernlife metabolic disorders such as diabetes, obesity, and cardiovascular diseases. Phosphorylation of PPARγ by the cyclindependent kinase 5 (Cdk5) has been recently proved to promote obesity and loss of insulin sensitivity.

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